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观察复方六一汤对环磷酰胺 (Cy)致血虚小鼠体重、脾重、脾指数及其组织学影响。结果发现 :血虚组小鼠净增体重、脾重、脾指数均小于正常对照组 ,并发现脾脏组织学结构有不同程度的损伤 ,白髓减少 ,结构紊乱 ,巨噬细胞、巨核细胞减少等。而在Cy基础上灌服复方六一汤的小鼠上述指标明显上升 ,脾脏组织学结构亦有修复好转。结果提示复方六一汤对脾具有扶健作用。
To observe the effect of Fufangliuyi Decoction on body weight, spleen weight, spleen index and histology of blood-deficient mice induced by cyclophosphamide (Cy). The results showed that the net body weight, spleen weight and spleen index of mice in blood deficiency group were less than that of normal control group, and the histological structure of spleen was found to have different degrees of damage, white pulp reduction, structural disorder, reduction of macrophages and megakaryocytes . On the basis of Cy-based compound Liuyi Tang mice significantly increased the above indicators, the spleen histological structure also improved repair. The results suggest that Fufang Liuyi Decoction can improve the spleen.