目的探讨心脏黏液瘤的临床治疗和预后。方法回顾分析2001-01-2010-01 95例心脏黏液瘤患者临床资料。结果 95例均接受手术治疗。本组围术期死亡3例,死因分别为术后低心输出量综合征2例、应激性溃疡及大面积脑栓塞各1例,围术期病死率为3.16%。术后并发房性心律失常7例、心包积液3例、下肢栓塞1例。出院患者中86例进行出院后随访,仅2例分别在术后3 a及9 a复发,1例为多发性黏液瘤、1例为左房壁黏液瘤。另有1例死于急性肾功能衰竭、慢性充血性心衰。结论心脏黏液瘤只要能够切除,预后是良好的,手术切除是治疗心脏黏液瘤首选的治疗方法。术后随访复查非常重要。心脏黏液瘤手术后复发率低,远期复发可能与其起源部位有关。 Objective To investigate the clinical treatment and prognosis of cardiac myxoma. Methods The clinical data of 95 patients with cardiac myxomas from January 2001 to March 2010 were retrospectively analyzed. Results All 95 cases received surgical treatment. Three patients died in the perioperative period. The cause of death was postoperative low cardiac output syndrome in 2 patients, stress ulcer, and large area cerebral embolism in 1 patient. The perioperative mortality was 3.16%. Postoperative atrial arrhythmias occurred in 7 cases, pericardial effusion in 3 cases, and lower extremity embolism in 1 case. 86 patients discharged from the hospital were followed up after discharge. Only 2 cases recurred at 3 and 9 months postoperatively. One patient had multiple myxoma and one patient had left atrial myxoma. Another case died of acute renal failure and chronic congestive heart failure. Conclusion As long as the cardiac myxoma can be removed, the prognosis is good. Surgical resection is the preferred treatment for cardiac myxoma. Postoperative follow-up review is very important. The recurrence rate of cardiac myxoma after surgery is low, and the long-term recurrence may be related to its origin.