患者,男性,35岁。自出生时背部有一鸡卵大的白色斑片,9岁时面部出现红色小丘疹,渐增多增大,不痛不痒。近5年来,下肢及背部起淡红色斑块,指趾甲相继出现多量赘生物,均无任何感觉。无癫痫病史。父母非近亲婚配,无同样病史。体格检查:系统检查无异常。智力正 Patient, male, 35 years old. Since the birth of a large white chicken eggs, at the age of 9 red papules appear on the face, increasing increased, insignificant. In the recent 5 years, the lower limbs and back have light red patches, which means the nails have a large amount of neoplasm successively without any feeling. No history of epilepsy. Parents non-relatives marriage, no history of the same. Physical examination: No abnormalities in the system examination. Intelligence is positive