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目的观察糖尿病肾病早期血清胱抑素C与肌酐的变化,评价胱抑素C在糖尿病肾病早期的应用价值。方法将69例糖尿病肾病早期患者与70例正常健康体检者分为两组,测定肌酐和胱抑素C。结果糖尿病肾病组较正常对照组胱抑素C有显著增高(P<0.05),肌酐无显著增高(P>0.05)。结论血清胱抑素C较肌酐在糖尿病肾病早期的诊断中更为敏感准确。
Objective To observe the changes of serum cystatin C and creatinine in the early stage of diabetic nephropathy and evaluate the value of cystatin C in the early stage of diabetic nephropathy. Methods 69 patients with early diabetic nephropathy and 70 normal healthy subjects were divided into two groups, creatinine and cystatin C were measured. Results Compared with normal control group, the level of cystatin C in diabetic nephropathy group was significantly increased (P <0.05) and creatinine was not significantly increased (P> 0.05). Conclusion Serum cystatin C is more sensitive and accurate than creatinine in the early diagnosis of diabetic nephropathy.