论文部分内容阅读
目的探讨老年结核病患者抗结核治疗的的临床效果和不良反应,进一步指导老年结核病的治疗。方法选择我院门诊和住院部在2010年3月—2012年3月之间收治的老年结核病患者100例作为研究对象,采用抗结核药物进行治疗,对治疗的临床效果及不良反应发生情况进行观察和记录,对临床资料进行回顾性总结分析。结果本组100例患者,经过我院积极抗结核治疗,临床症状显著改善,影像检查病灶吸收、钙化、空洞变小等,治疗总有效率为(90%);共发生不良反应30例,其中胃肠道反应20例,肝损害7例,尿酸升高、关节肿痛5例,过敏反应4例(异烟肼1例、利福平2例),6例患者出现肝功能损坏、胃肠道反应等混合不良反应,不良反应发生率为30%。结论采用抗结核药物治疗老年结核病,具有一定的临床疗效,但不良反应较多,需要谨慎使用。
Objective To explore the clinical effects and adverse reactions of anti-TB therapy in elderly patients with tuberculosis and further guide the treatment of elderly patients with tuberculosis. Methods A total of 100 elderly patients with tuberculosis were selected from outpatient department and inpatient department between March 2010 and March 2012 as study subjects and treated with anti-TB drugs. The clinical effects and adverse reactions were observed And records, retrospective analysis of clinical data. Results The total effective rate was (90%) in 100 patients in our hospital after active anti-TB treatment in our hospital. The clinical symptoms were significantly improved. The total effective rate of the treatment was (90%). There were 30 adverse reactions Gastrointestinal reactions in 20 cases, liver damage in 7 cases, uric acid increased, joint swelling and pain in 5 cases, 4 cases of allergic reactions (isoniazid in 1 case, 2 cases of rifampicin), 6 patients with liver damage, gastrointestinal Road reaction mixed adverse reactions, the incidence of adverse reactions was 30%. Conclusion The anti-tuberculosis drugs for the treatment of elderly patients with tuberculosis have some clinical efficacy, but more adverse reactions, need to be used with caution.