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对41例卵巢恶性肿瘤,30例卵巢良性肿瘤进行外周血T细胞亚群、NK细胞活性检测,并与30例健康者对照。结果:①恶性组T4、T4/T8比值明显低于良性组及对照组(P<0.05),后两者之间无明显差异。肿瘤细胞减灭术后2周,水平上升,较术前有显著差异(P<0.05)。②恶性组NK细胞活性明显低于良性组及对照组。随病情进展进一步降低,临床Ⅲ~Ⅳ期明显低于Ⅰ~Ⅱ期(P<0.05)。提示检测上述指标具有重要临床意义。
In 41 cases of ovarian cancer and 30 cases of benign ovarian tumors, T lymphocyte subsets and NK cell activity were detected in peripheral blood and 30 healthy controls. Results: ① The ratio of T4, T4 / T8 in malignant group was significantly lower than that in benign group and control group (P <0.05), but there was no significant difference between the two groups. Tumor cytoreductive surgery two weeks after the rise, compared with the preoperative significant difference (P <0.05). The malignant group NK cell activity was significantly lower than the benign group and the control group. With the progression of the disease to further reduce the clinical stage Ⅲ ~ Ⅳ was significantly lower than Ⅰ ~ Ⅱ (P <0.05). Tip detection of the above indicators of great clinical significance.