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为了观察消化性溃疡患者血清胃泌素的含量及其临床意义,笔者分别测定了消化性溃疡患者活动期、愈合期和正常人血清胃泌素的含量,并对它们之间的关系进行分析讨论。1 对象和方法1.1 研究对象1.1.1 消化性溃疡活动期组58例,男47例,女11例.年龄12～76岁,均为住院或门诊病人,经纤维胃镜证实为消化性溃疡(十二指肠球部溃疡37例,胃溃疡27例,其中复合溃疡6例)。且在2周内未用过任何抗酸剂、H_2-受体阻断剂、泵抑制剂及抗胆碱类药物。无心、肝、肾、肺等严重内科疾病,亦未行过胃部及迷走神经手术。1.1.2 治疗后愈合期组20例,男18例,女2例。均为活动期组内经抗溃疡正规治疗,2到3月后胃镜复查达到溃疡疤痕期(S_1或S_2期)。近1年内无发作,3月内未服用抗酸类药物者。1.1.3 正常对照组50例,男33例,女17例。年龄24～的岁。本组均为健康体检者,均无消化系统症状及疾病。
In order to observe the content of serum gastrin in patients with peptic ulcer and its clinical significance, we measured the content of serum gastrin in patients with peptic ulcer during active phase, healing phase and normal person respectively, and analyzed the relationship between them . 1 Subjects and Methods 1.1 Subjects 1.1.1 active peptic ulcer group of 58 cases, 47 males and 11 females aged 12 to 76 years, were hospitalized or outpatient confirmed by gastroscopy peptic ulcer (ten 37 cases of duodenal ulcer, gastric ulcer in 27 cases, including 6 cases of complex ulcer). And in 2 weeks without any antacids, H 2 -receptor blockers, pump inhibitors and anticholinergic drugs. No heart, liver, kidney, lung and other serious medical problems, but also did not go through the stomach and vagus nerve surgery. 1.1.2 healed after treatment group of 20 cases, 18 males and 2 females. All patients were active in the anti-ulcer group by regular treatment, 2 to 3 months after the endoscopy to ulcer scars (S_1 or S_2 phase). No seizures within the past year, not taken within 3 months of anti-acid drugs. 1.1.3 normal control group of 50 patients, 33 males and 17 females. Age of 24 ~ years old. This group are healthy people, no digestive system symptoms and diseases.