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目的探讨2型糖尿病患者采用药物治疗的方法及疗效。方法选取2013年1月至2014年7月长春市绿园区人民医院收治的2型糖尿病患者160例为研究对象,按随机数字表法分为4组,每组40例。第1组患者采用二甲双胍片治疗,第2组患者采用格列美脲片治疗,第3组患者采用阿卡波糖治疗,第4组患者采用格列齐特治疗,比较4组治疗前后的各项血糖值和不良反应发生情况。结果 4组患者用药治疗后的空腹血糖、餐后2 h血糖和糖化血红蛋白水平均明显低于治疗前,差异均有统计学意义(均P<0.05);第1组患者不良反应发生率明显低于其他3组,差异有统计学意义(P<0.05)。结论 2型糖尿病患者采用二甲双胍、格列美脲片、阿卡波糖和格列齐特进行治疗,其治疗效果均比较理想,二甲双胍的疗效更佳、不良反应发生率更低,可作为2型糖尿病的首选药物。
Objective To investigate the method and effect of medication in type 2 diabetic patients. Methods From January 2013 to July 2014, 160 patients with type 2 diabetes admitted to Lvyuan District People’s Hospital of Changchun were divided into 4 groups (n = 40) according to random number table. The patients in group 1 were treated with metformin tablets, the patients in group 2 were treated with glimepiride tablets, the patients in group 3 were treated with acarbose, the patients in group 4 were treated with gliclazide, and the patients in each group before and after treatment Item blood sugar levels and adverse reactions. Results The fasting blood glucose, postprandial 2-h blood glucose and glycosylated hemoglobin in the 4 groups were significantly lower than those before treatment (all P <0.05). The incidence of adverse reactions in group 1 was significantly lower In the other three groups, the difference was statistically significant (P <0.05). Conclusion Patients with type 2 diabetes treated with metformin, glimepiride tablets, acarbose and gliclazide, the treatment effect is ideal, the efficacy of metformin is better, the incidence of adverse reactions is lower, can be used as type 2 The drug of choice for diabetes.