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目的分析泌尿道感染患者病原菌的分布特点及耐药现状，为临床合理使用抗菌药物提供依据。方法细菌鉴定采用ATB EXPRESSION细菌鉴定系统，药敏试验采用纸片扩散法(K-B法)，用WHONET5.6软件进行耐药性分析。结果1530例分离菌株中，革兰阴性杆菌1108株，占72.42%；革兰阳性球菌279株，占18.24%；真菌143株，占9.34%。大肠埃希菌711株，是泌尿道感染的主要致病菌，占46.47%。结论大肠埃希菌仍是泌尿道感染的主要病原菌，碳青霉烯类耐药的肠杆菌科细菌和VRE的感染应引起重视。“,”Objective To analyze the distribution characteristics of patients with urinary tract infection pathogens and drug resistance status, provide the basis for clinical rational use of antimicrobial agents. Methods Bacteria identified by ATB EXPRESSION bacteria identification system, drug sensitive test by disc dif usion method (K- B method), with WHONET5.6 software for drug resistance analysis. Results 1530 cases of isolated strains, gram-negative bacil i 1108 strains, accounting for 72.42%;279 strains were gram positive coccus, accounting for 18.24%;Fungus 143 strains, accounting for 9.34%. 711 strains of e. coli, is the main pathogenic bacteria of urinary tract infection, accounting for 46.47%. Conclusion e. coli is stil the main pathogenic bacteria in urinary tract infection, penicil ium carbon alkene resistant enterobacteriaceae bacteria and VRE infections should be taken into consideration seriously.