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O-聚糖在肿瘤细胞中其结构会发生异常,并与癌细胞的表型及生物学特性密切相关[1]。多肽N-乙酰氨基半乳糖转移酶2(pp-Gal NAcT2)催化O-聚糖合成的第一步。本文研究其在不同肿瘤细中的差异表达,以探索其在肿瘤发生、发展中的作用。材料与方法1·材料NI H3T3成纤维细胞、胃癌细胞?
The structure of O-glycans in tumor cells will be abnormal, and with the cancer cell phenotype and biological characteristics are closely related [1]. Peptide N-acetylgalactosaminyltransferase 2 (pp-Gal NAcT2) catalyzes the first step in the synthesis of O-glycans. In this paper, we study its differential expression in different tumor types to explore its role in tumorigenesis and development. Materials and Methods 1. Materials NI H3T3 fibroblasts, gastric cancer cells?