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一切生命现象几乎都在酶的催化下进行,各种代谢异常性疾病无不与酶的失调有关,有些先天性代谢障碍就是由于溶酶体中某些酶的缺乏。酶类药物通常具有作用明确、专一性强、疗效显著等特点,所以愈来愈广泛地用于疾病的预防和治疗。来源于动物、微生物或植物体的酶制品都是人体的异种蛋白,使用时存在着明显缺点:(1)纯制手续繁杂,价格昂贵;(2)在人体内的吸收、分布局限性很大,尤其难于通过血脑屏
Almost all life phenomena are catalyzed by enzymes, all kinds of metabolic disorders are related to the imbalance of enzymes, and some congenital metabolic disorders are due to the lack of certain enzymes in lysosomes. Enzymes usually have a clear role, specificity, significant effect and so on, so more and more widely used in the prevention and treatment of diseases. Enzyme products derived from animals, microorganisms or plants are all xenogenic proteins of the human body. There are obvious shortcomings when used: (1) complex and expensive purification procedures; (2) large absorption and distribution in the human body , Especially difficult to pass the blood-brain screen