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目的了解甘肃省白银市公共场所从业人员甲型和戊型肝炎的感染状况,为进一步完善体检项目及预防控制工作提供科学依据。方法选取2011─2014年白银市公共场所从业体检人员8 079人,抽取体检者空腹静脉血3~5ml,用酶联免疫(ELISA)法检测HAV-IgM和HEV-IgM。结果 2011─2014年白银市公共场所从业人员HAV-IgM、HEV-IgM平均阳性率分别为0.11%、0.06%;检出HAV-IgM、HEV-IgM阳性例数集中在20~40岁青壮年组,不同年龄组间HAV-IgM(χ2=2.554)、HEV-IgM(χ2=1.006)阳性率差异均无统计学意义(P>0.05);HAV-IgM阳性率男性0.27%、女性0.05%,差异有统计学意义(χ2=4.925,P<0.05)。结论白银市公共场所从业人员HAV-IgM、HEV-IgM阳性检出率虽较一些城市低,但仍检出阳性个体,应重视并坚持对其开展预防性健康体检工作;为保证检测结果的准确性,在检测IgM抗体的基础上应同时检测Ig G抗体。
Objective To understand the status of hepatitis A and hepatitis E infection in public places in Baiyin, Gansu Province, and provide a scientific basis for further improvement of the physical examination items and prevention and control. Methods A total of 8 079 medical employees in public places in Baiyin City from 2011 to 2014 were selected. Fasting venous blood samples were collected from 3 to 5 ml, and HAV-IgM and HEV-IgM were detected by enzyme-linked immunosorbent assay (ELISA). Results The average positive rates of HAV-IgM and HEV-IgM in public places in Baiyin from 2011 to 2014 were 0.11% and 0.06% respectively. The positive cases of HAV-IgM and HEV-IgM were detected in young adults aged 20-40 years The positive rates of HAV-IgM (χ2 = 2.554) and HEV-IgM (χ2 = 1.006) in different age groups were not significantly different (P> 0.05) .The positive rate of HAV-IgM was 0.27% in male and 0.05% in female, There was statistical significance (χ2 = 4.925, P <0.05). Conclusion Although positive rates of HAV-IgM and HEV-IgM in public places in Baiyin City are lower than those in some cities, positive individuals are still detected. Therefore, preventive health examination should be paid attention to and persisted. To ensure the accuracy of the test results Sex, in the detection of IgM antibodies should be based on the simultaneous detection of Ig G antibodies.