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为研究急性心肌梗塞（ＡＭＩ）超急性期压力反射敏感性（ＢＲＳ）的动态变化规律，制备了ＳＤ大鼠ＡＭＩ模型，观察以ＡＭＩＯ～４ｈ的ＢＲＳ变化及其与血流动力学改变的关系，发现ＡＭＩ３０分钟时即有ＢＲＳ钝化现象，以１ｈ时最为明显。ＢＲＳ钝化与ＢＰ及心脏功能无关。
To investigate the dynamic changes of hypersensitivity to baroreflex (BRS) in acute myocardial infarction (AMI), an AMI model of SD rats was prepared. The changes of BRS in AMIO ~ 4h and its relationship with hemodynamic changes were observed. Found AMI 30 minutes BRS passivation phenomenon, the most obvious at 1h. BRS passivation has nothing to do with BP and heart function.