论文部分内容阅读
探讨了增殖细胞核抗原 (PCNA)、p5 3、端粒酶、ras蛋白等作为胃癌早期诊断分子生物学指标的可能性。通过对文献的分析 ,发现 PCNA、p5 3是胃癌早期诊断应当首先考虑的分子生物学指标 ,它们可用简单的免疫组化方法方便地测得。端粒酶也是一个很好的指标 ,只是由于其检测方法不够方便 ,价格较贵 ,故可行性不如前两个指标。此外 ,ras也可以考虑作为胃癌早期诊断的辅助指标。
The possibility of proliferating cell nuclear antigen (PCNA), p53, telomerase, and ras proteins as molecular markers for the early diagnosis of gastric cancer was investigated. Through analysis of the literature, it was found that PCNA and p53 are molecular biological indicators that should be considered first in the early diagnosis of gastric cancer. They can be easily measured by a simple immunohistochemical method. Telomerase is also a good indicator, but because its detection method is not convenient and expensive, it is not as viable as the first two indicators. In addition, ras can also be considered as an auxiliary indicator for the early diagnosis of gastric cancer.