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目的:探讨妊娠期高血压综合征患者血清钙、镁及LDL-C、IL-8、脂联素、MMP-9水平变化规律。方法:选取2008年6月～2009年12月于该院进行治疗的62例妊娠期高血压综合征患者为研究观察组,同时选取同期的62例健康孕妇为对照组,将两组孕妇的血清钙、镁及LDL-C、IL-8、脂联素、MMP-9水平进行检测及比较。结果:观察组的血清钙、镁、脂联素、MMP-9水平低于对照组,血清LDL-C、IL-8水平高于对照组,且随疾病的加重波动幅度越来越大,经比较,P<0.05或P<0.01,有统计学差异。结论:妊娠期高血压综合征患者血清钙、镁及LDL-C、IL-8、脂联素、MMP-9水平均呈现一定的波动幅度,可为其诊断及治疗提供依据。
Objective: To investigate the changes of serum calcium, magnesium, LDL-C, IL-8, adiponectin and MMP-9 in patients with pregnancy-induced hypertension. Methods: Sixty-two patients with pregnancy-induced hypertension (Hypertension syndrome) treated in our hospital from June 2008 to December 2009 were selected as the study group. Sixty-two healthy pregnant women in the same period were selected as the control group. Serum Calcium, magnesium and LDL-C, IL-8, adiponectin, MMP-9 levels were detected and compared. Results: The levels of serum calcium, magnesium, adiponectin and MMP-9 in the observation group were lower than those in the control group, and the levels of serum LDL-C and IL-8 in the observation group were higher than those in the control group. P <0.05 or P <0.01, with statistical significance. Conclusion: The levels of serum calcium, magnesium, LDL-C, IL-8, adiponectin and MMP-9 in patients with pregnancy-induced hypertension show some fluctuations, which may provide the basis for its diagnosis and treatment.