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目的探讨坐骨海绵体肌在勃起机制中的地位和作用。为临床诊断和治疗骨盆骨折并尿道损伤后的勃起功能障碍是否与坐骨海绵体肌损伤有关提供依据。方法选用生殖期雄性大白鼠35只,随机分为手术组(25只)、假手术组(5只)和非手术组(5只)。将手术组切断双侧坐骨海绵体肌,假手术组仪显露坐骨海绵体肌后关闭切口。手术1周后选用育龄期雌性大白鼠35只,随机与上述三组——配对饲养。观察2月,了解三组配对雌鼠受孕情况。随后将手术组分为修复组(17对)和未修复组(5对),将修复组雄鼠修复其切断的双侧坐骨海绵体肌,未修复组作对照。观察2月,了解配对雌鼠受孕情况。结果手术组雄鼠死亡2只,雌鼠1只受孕,受孕率为4．35％,假手术组雄鼠死亡1只,雌鼠4只受孕,受孕率为100％,非手术组雌鼠5只均受孕,受孕率为100％,修复组雄鼠死亡9只,存活8只,其配对雌鼠2只受孕,受孕率为25％,未修复组5只雌鼠均未受孕,受孕率为0。手术组与假手术组、非手术组雌鼠受孕情况比较有统计学意义(P<0．001),假手术组与非手术组比较无统计学意义,修复组与未修复组比较无统计学意义(P>0．05)。结论切断雄鼠双侧坐骨海绵体肌必然导致勃起功能障碍,引起不育。坐骨海绵体肌在阴茎勃起机制中是勃起过程中的一个环节,不可缺少,其作用是起控制阴茎勃起血流的闸门或开关的作用。
Objective To investigate the status and function of ischial sponge muscle in erectile mechanism. To provide a basis for clinical diagnosis and treatment of pelvic fractures and urethral injury after erectile dysfunction and sciatica muscle injury. Methods 35 reproductive male rats were randomly divided into operation group (n = 25), sham operation group (n = 5) and non-operation group (n = 5). The operation group was cut bilateral ischial sponge muscle, sham operation group revealed ischial sponge muscle closed incision. One week after surgery, 35 female reproductive age females were randomly assigned to the above three groups - paired feeding. Observed in February, understand the pregnancy of three groups of female counterparts. The operation group was divided into the repair group (17 pairs) and the uncoated group (5 pairs), and the repaired group was repaired with the sequestered bilateral ischial cavernosus muscle. The uncorrected group served as a control. Observed in February to understand the mating female mice conception. Results Two males died in the surgery group, one females were pregnant, the pregnancy rate was 4.35%, one males died in the sham operation group, four females were pregnant, the pregnancy rate was 100%, the non-operation females 5 Only conceive, the pregnancy rate was 100%, the repair group males died 9, survived 8, the mating females 2 conception, pregnancy rate was 25%, 5 non-repaired group of females were not pregnant, pregnancy rate was 0. There were significant differences in the pregnancy status between the operation group and the sham operation group and the non-operation group (P <0.001), but there was no significant difference between the sham operation group and the non-operation group Significance (P> 0.05). Conclusion Severing both sides of the sciatic cavernous muscles of the male will inevitably lead to erectile dysfunction and cause infertility. Ischia sponge muscle erectile mechanism in the penis is an integral part of the process of erection, its role is to control the penile erection of blood flow gate or switch role.