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[目的]了解磁县上消化道癌第二轮早期筛查癌前状态及病变的检出率情况。[方法]收集2014年完成的40~69岁人群的上消化道癌内镜筛查资料,对符合对象按性别、年龄组统计食管、贲门、远端胃癌前状态及病变的检出率。[结果]纳入分析筛查对象2417例,食管活检率为26.85%,贲门活检率为12.37%,胃活检率为28.59%。食管癌及各级病变检出率分别为:鳞状上皮轻度异型增生检出率为3.52%,鳞状上皮中度异型增生检出率为0.91%,鳞状上皮重度异型增生检出率为0.70%,原位癌检出率为0.41%,黏膜内鳞状细胞癌检出率为0.17%,浸润性鳞癌检出率为0.04%,总体阳性检出率为1.32%。贲门癌及癌前病变检出率分别为:低级别上皮内肿瘤检出率为0.62%,高级别上皮内肿瘤检出率为0.17%,黏膜内腺癌检出率为0.29%,浸润性腺癌检出率为0.04%,总体阳性检出率为0.50%。远端胃癌及癌前病变检出率分别为:低级别上皮内肿瘤检出率为1.45%,高级别上皮内肿瘤检出率为0.04%,浸润性腺癌检出率为0.04%,总体阳性检出率为0.08%。[结论]2014年度总体检出率与10年前首次筛查资料相比明显有所下降,食管、贲门及远端胃的低级别上皮内肿瘤的检出率较低,与活检率及活检块数有一定的关系。
[Objective] To understand the second round of screening of precancerous lesions and the detection rate of upper digestive tract cancer in Cixian county. [Methods] The data of endoscopic upper gastrointestinal cancer screening in 40 ~ 69 years old population completed in 2014 were collected. The detection rates of esophageal, cardial and distal gastric precancerous lesions and lesions of the matched subjects by sex and age group were collected. [Results] 2417 cases were included in the analysis, the esophageal biopsy rate was 26.85%, the cardia biopsy rate was 12.37%, and the gastric biopsy rate was 28.59%. The detection rates of esophageal cancer and lesions at all levels were as follows: the detection rate of mild dysplasia in squamous epithelium was 3.52%, the detection rate of moderate dysplasia in squamous epithelium was 0.91%, the detection rate of severe dysplasia in squamous epithelium was 0.70%, the rate of carcinoma in situ was 0.41%, the rate of squamous cell carcinoma in mucosa was 0.17%, the rate of invasive squamous cell carcinoma was 0.04% and the overall positive rate was 1.32%. Cardiac cancer and precancerous lesions were detected: low-grade intraepithelial tumor detection rate was 0.62%, high-grade intraepithelial tumor detection rate was 0.17%, mucosal adenocarcinoma detection rate was 0.29%, invasive adenocarcinoma The detection rate was 0.04%, the overall positive detection rate was 0.50%. The detection rates of distal gastric cancer and precancerous lesions were 1.45% for low-grade intraepithelial neoplasms, 0.04% for high-grade intraepithelial neoplasms, 0.04% for invasive adenocarcinoma, and overall positive test The rate is 0.08%. [Conclusion] The overall detection rate in 2014 was significantly lower than that of the first screening data 10 years ago. The detection rate of low grade intraepithelial neoplasms in the esophagus, cardia and distal stomach was lower, and the biopsy rate and biopsy mass There are a number of relations.