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HBe抗原在乙型肝炎病毒(HBV)感染中的重要意义,正日益增加。已经知道HBe抗原阳性血中含有大量的HBV而且感染性强,加上最近又弄清了HBV持续感染的病理状态与HBe抗原的关系,使HBe抗原受到了新的重视。这里试对HBe抗原的意义,整理如下: 1.作为感染性的标记日本通过对黑猩猩的感染性试验,弄清了HBe抗原阳性血清的感染力,比HBe抗体血清约强10~8倍。已经知道在母婴感染时,HBe抗原阳性病毒携带者母亲所生的婴儿,有80～90%成为携带者。关于婴儿的携带者形成率问题,需详细说明。如果母体血的HBe抗原是用灵敏度低的方法调查的,结果是当母亲为HBe抗原阳性时,婴儿成为携带者的比率很高,但
The significance of HBe antigen in hepatitis B virus (HBV) infection is increasing. It has been known that HBe antigen-positive blood contains a large amount of HBV and is highly infectious. In addition, recently, the relationship between the pathological state of persistent HBV infection and HBe antigen has been recognized, and new emphasis has been placed on HBe antigen. The significance of HBe antigen test here, organized as follows: 1. As an infectious marker Japan through the chimpanzees infectious test, clear HBe antigen-positive serum infectivity, HBe antibody serum about 10 to 8 times stronger. It is known that from 80 to 90% of babies born to mothers with HBe antigen-positive mothers become carriers when they are infected. The baby’s carrier formation rate of the problem, to be detailed. If the HBe antigen in maternal blood is investigated with a less sensitive method, the result is a high rate of infancy becoming a carrier when the mother is HBe antigen positive