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目的比较多索茶碱与氨茶碱治疗支气管哮喘的临床疗效。方法选取2012年3月—2013年5月柳林县人民医院收治的支气管哮喘患者210例,按随机数字表法分为观察组和对照组,各105例。两组均给予常规综合治疗,对照组予以氨茶碱治疗,观察组予以多索茶碱治疗。观察两组患者的临床疗效、不良反应发生率及肺功能。结果观察组总有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。观察组第1秒用力呼气末容积(FEV1)、用力肺活量(FVC)、肺活量(VC)高于对照组,差异有统计学意义(P<0.05)。结论多索茶碱治疗支气管哮喘的临床疗效优于氨茶碱,可更好地改善患者临床症状,且不良反应少。
Objective To compare the clinical efficacy of doxofylline and aminophylline in the treatment of bronchial asthma. Methods 210 patients with bronchial asthma admitted to Liulin County People’s Hospital from March 2012 to May 2013 were randomly divided into observation group and control group with 105 cases in each group. Both groups were given conventional comprehensive treatment, the control group was treated with aminophylline, the observation group was treated with doxofylline. The clinical efficacy, incidence of adverse reactions and pulmonary function in two groups were observed. Results The total effective rate of the observation group was higher than that of the control group, and the incidence of adverse reactions was lower than that of the control group (P <0.05). FEV1, FVC and VC in the observation group were significantly higher than those in the control group (P <0.05). Conclusion Doxofylline is superior to aminophylline in the treatment of bronchial asthma, which can improve the clinical symptoms of patients with less adverse reactions.