血液系统恶性疾病患者由于疾病本身以及使用化疗药物、大剂量免疫抑制剂后常出现严重感染,反复大量使用广谱抗生素后又易并发侵袭性真菌感染,并成为血液系统恶性疾病长期发热的主要原因之一。近5年来我们对长期发热、确诊或拟诊为侵袭性真菌感染的58例血液系统恶性疾病患者采用 Due to the disease itself and the use of chemotherapy drugs, patients with hematologic malignancies often have severe infections after high-dose immunosuppressive agents. Repeated extensive use of broad-spectrum antibiotics is also prone to complicated invasive fungal infections and become the main cause of long-term fever in hematological malignancies one. In the past five years, we used 58 patients with hematologic malignancies who had long-term fever, confirmed or suspected invasive fungal infection