补体旁路途径在肾小球疾病中的作用机制在近10年有突性进展,过去认为这一途径仅仅在免疫复合物形成及沉积中作用的观点受到挑战,新的研究发现补体旁路途径在肾小球病的发生、发展中有着其独立的作用,并得到动物实验及临床料证实。对补体系统在肾小球疾病中的作用机制的深入研究示,各类补体抑制药物可为相关疾病的治疗提供可能。现就 Complement pathway pathway in glomerular disease mechanism of sudden progress in the past 10 years, in the past that this pathway only in the immune complex formation and deposition of the role of challenge, the new study found that complement bypass pathway In the occurrence of glomerular disease, the development has its own independent role, and animal experiments and clinical materials confirmed. The in-depth study of the mechanism of action of the complement system in glomerular diseases shows that various types of complement inhibitory drugs may provide the possibility for the treatment of related diseases. Now