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目的研究中老年尿毒症患者肾移植前、后左室结构和功能的改变。方法经胸彩色多普勒超声心动图测量20例中老年尿毒症患者肾移植前、肾成功移植三个月以后的左室结构及功能。结果中老年尿毒症患者移植前后心脏各参数左室舒末径、左室壁厚度、左室收缩及舒张功能均有明显改善(P<0.05);肾移植后三个月左室壁厚度较移植术前明显减小(P<0.01),仍较正常对照组增厚(P<0.05),其余指标与正常对照组无明显差异(P>0.05)。结论中老年尿毒症患者在成功进行肾移植术后,左室的结构及功能均得以改善。
Objective To study the changes of left ventricular structure and function before and after renal transplantation in middle-aged and aged uremic patients. Methods Thoracic color Doppler echocardiography was used to measure left ventricular structure and function in 20 cases of middle-aged and aged patients with uremia before kidney transplantation and three months after successful transplantation. Results Left ventricular diastolic dimension, left ventricular wall thickness, left ventricular systolic and diastolic function were significantly improved in middle-aged and elderly patients with uremia before and after transplantation (P <0.05). Left ventricular wall thickness (P <0.01), still thicker than the normal control group (P <0.05), and the other indexes had no significant difference with the normal control group (P> 0.05). Conclusion The structure and function of the left ventricle can be improved after middle and old aged patients with uremia successfully undergo renal transplantation.