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目的:探讨液基薄层细胞学技术(TCT)在宫颈病变筛查中的诊断价值及临床意义。方法:对我院2010年8月到2011年12月门诊4732例育龄妇女进行宫颈液基薄层细胞学检测,将结果为不典型鳞状细胞-意义不明(ASC-US)或不典型腺细胞(AGUS)以上病变行阴道镜下活检,将细胞学检测结果与活检结果作对比分析。结果4732例TCT检测的育龄妇女中,标本满意度99.37%。宫颈不典型细胞-意义不明(ASC-US)以上病变412例,占8.71%。对ASC-US以上的412例异常者进行阴道镜下活检,组织病理诊断结果炎症198例,低度鳞状上皮内病变(LSIL)178例,高度鳞状上皮内病变(HSIL)29例,鳞状细胞癌(SCC)5例、腺癌(AC)2例。结论:TCT可早期发现宫颈癌前病变,阳性病例配合阴道镜活检可进一步明确诊断。
Objective: To investigate the diagnostic value and clinical significance of liquid-based thin-layer cytology (TCT) in cervical lesions screening. Methods: A total of 4732 women of childbearing age at our outpatient clinic from August 2010 to December 2011 were examined by liquid-based thin-layer cytology. The results were atypical squamous cell-ASC-US or atypical glandular cells AGUS) over the line colposcopy biopsy, the cytology test results and biopsy results for comparative analysis. Results Of 4732 women of childbearing age who were tested by TCT, the satisfaction of the specimens was 99.37%. Cervical atypical cells - unknown meaning (ASC-US) more than 412 cases of lesions, accounting for 8.71%. Colposcopic biopsy was performed on 412 cases of abnormal ASC-US, including 198 cases of pathological diagnosis of inflammation, 178 cases of low grade squamous intraepithelial lesion (LSIL), 29 cases of high grade squamous intraepithelial lesion (HSIL) 5 cases of squamous cell carcinoma (SCC) and 2 cases of adenocarcinoma (AC). Conclusion: TCT early detection of cervical precancerous lesions, positive cases with colposcopy biopsy can further confirm the diagnosis.