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目的探讨呋塞米联合依那普利治疗慢性肺源性心脏病并发心力衰竭的疗效。方法选取2014年5月~2016年3月我院收治的慢性肺源性心脏病并发心力衰竭患者86例,依据随机数表法分为观察组(呋塞米+依那普利)和对照组(常规治疗),比较两组患者的临床疗效、动脉血气分析结果及肺功能。结果观察组43例,其中显效33例(76.74%),有效8例(18.60%),无效2例(4.65%),总有效率为95.35%;对照组43例,其中显效20例(46.51%),有效15例(34.88%),无效8例(18.60%),总有效率为81.40%。治疗后,观察组患者的Pa O2、Sa O2明显高于对照组,Pa CO2显著低于对照组(P<0.05)。治疗后,观察组患者的FEV1、FVC、FEV1/FVC均明显升高(P<0.05)。结论呋塞米联合依那普利治疗慢性肺源性心脏病并发心力衰竭成效显著,能够明显改善患者肺功能,纠正心力衰竭。
Objective To investigate the curative effect of furosemide plus enalapril in the treatment of patients with chronic cor pulmonale complicated with heart failure. Methods From May 2014 to March 2016, 86 patients with chronic cor pulmonale complicated with heart failure admitted to our hospital were divided into observation group (furosemide plus enalapril) and control group according to random number table (Routine treatment), the clinical efficacy of two groups of patients, arterial blood gas analysis results and lung function. Results The observation group consisted of 43 cases (76.74%), 8 (18.60%) effective and 2 (4.65%) ineffective with a total effective rate of 95.35% ), Effective in 15 cases (34.88%), invalid in 8 cases (18.60%), the total effective rate was 81.40%. After treatment, Pa O2 and Sa O2 in the observation group were significantly higher than those in the control group, Pa CO2 was significantly lower than that in the control group (P <0.05). After treatment, FEV1, FVC and FEV1 / FVC in the observation group were significantly increased (P <0.05). Conclusions Furosemide combined with enalapril treatment of chronic pulmonary heart disease complicated by heart failure has achieved remarkable results, which can significantly improve pulmonary function and correct heart failure.