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目的了解杭州市儿童手足口病发病的危险因素。方法在杭州4家医院,对临床诊断为手足口病患儿进行采样检测。130例实验室诊断为手足口病病例为病例组,同期在同所医院就诊非感染性疾病患儿作为对照组。制定统一的调查表进行调查,资料采用SPSS 13.0软件单因素和多因素非条件logistic回归分析。结果单因素分析结果有统计学意义的变量包括流动人口、大小便能自理、便后洗手、看护人接受过防治知识及接触史共5项因素。多因素分析结果显示,流动人口(OR=2.266,95%CI:1.092~4.705)、共用玩具(OR=2.517,95%CI:1.160~4.009)、与患者有接触史(OR=21.698,95%CI:6.099~77.194)为促进因素;大小便能自理(OR=0.258,95%CI:0.141~0.472)为保护因素。结论接触传播是手足口病的主要传播方式,养成良好的卫生习惯对于控制手足口病的传播意义重大。
Objective To understand the risk factors of hand-foot-mouth disease in children in Hangzhou. Methods In 4 hospitals in Hangzhou, samples were collected from children with clinical diagnosis of hand-foot-mouth disease. 130 cases of laboratory diagnosis of hand-foot-mouth disease cases for the case group, over the same period in the same hospital for treatment of non-infectious diseases in children as a control group. To develop a unified questionnaire for investigation, data using SPSS 13.0 software univariate and multivariate non-conditional logistic regression analysis. Results The results of univariate analysis of the statistically significant variables include floating population, urine can take care of themselves, wash hands afterwards, the caregiver has received prevention and treatment of knowledge and history of a total of five factors. Multivariate analysis showed that there was a history of contact with patients (OR = 21.698, 95% CI, P0.05) in floating population (OR = 2.266,95% CI: 1.092-4.705) CI: 6.099 ~ 77.194) as the promotion factor; and urine and urine (OR = 0.258, 95% CI: 0.141 ~ 0.472) as protection factors. Conclusion The contact transmission is the main mode of transmission of hand-foot-mouth disease. Developing good health habits is of great significance for controlling the spread of hand-foot-mouth disease.