邓××,男,10岁,住院号152812。因不规则发热2年,伴肝脾肿大于1974年11月入本院儿科。患儿自幼体质较差,经常感冒发热。于1972年2月因发热在地段医院发现肝脾肿大。同年7月开始间歇性不规则发热,体温在38～40℃之间。用各种抗菌素无效。同年10月19日至11月16日,曾住上海某医院儿科,当时有发热,肝脾肿大。全身淋巴结肿大(1厘米左右)质中,经淋巴结穿刺及活检,未见到典型何杰金氏细胞,但在切片中发现少数分类不明细胞。蛋白电泳:γ球蛋白25.5％。乳胶试验(-)。有贫血,白细胞减少(1600～5900/立方毫米之间),血小板正常。临床上曾用多种抗菌素,疗效不显。在用强的松后,热才退至正常,肝脾明显缩小,全身淋巴结也缩小,因之出院。出院拟诊为网状细胞增生症。出院后不久,体温又常波动在37.5～39.7℃,肝脾又逐渐肿大而来本院。入院体检:颈部、腋下、腹股沟处可扪及蚕豆大之淋巴结,心肺(-),肝肋下4厘米,质中:脾肋下7厘米,质中等。神经系统(-)。实验室检查:血红蛋白6.8～9.9 Deng × ×, male, 10 years old, hospital number 152812. Due to irregular fever for 2 years, with hepatosplenomegaly greater than November 1974 into our hospital pediatrics. Children with poor health since childhood, often cold and fever. In February 1972 due to fever in the lot found in the hospital hepatosplenomegaly. In July the same year began intermittent irregular fever, body temperature between 38 ~ 40 ℃. With a variety of antibiotics invalid. The same year, October 19 to November 16, had a Shanghai pediatric hospital, was fever, hepatosplenomegaly. Lymphadenopathy (about 1 cm) in the mass, the lymph node biopsy and biopsy, did not see typical Hodgkin’s cells, but in the slice found a small number of unknown cells. Protein electrophoresis: gamma globulin 25.5%. Latex test (-). Anemia, leukopenia (1600 ~ 5900 / cubic millimeter), normal platelets. A variety of antibiotics have been used clinically, curative effect is not significant. After using the strong pine, the heat returned to normal, liver and spleen was significantly reduced, systemic lymph nodes also reduced, so discharged. Discharge is diagnosed as reticulocyte hyperplasia. Shortly after discharge, the body temperature often fluctuates between 37.5 and 39.7 ° C, and the liver and spleen are gradually swollen from the hospital. Admission examination: neck, armpit, groin palpable broad beans and lymph nodes, cardiopulmonary (-), liver ribs 4 cm, quality: spleen ribs 7 cm, medium quality. nervous system(-). Laboratory tests: hemoglobin 6.8 ~ 9.9