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目的研究分析不同高密度脂蛋白胆固醇(HDL-C)水平控制方案治疗冠心病的临床效果。方法 60例冠心病患者,随机分为对照组和观察组,各30例。对照组采用常规饮食控制治疗,观察组在对照组基础上给予烟酸缓释胶囊联合他汀类药物治疗。比较患者两组治疗效果。结果治疗前,两组胆固醇、甘油三酯、HDL-C水平比较,差异无统计学意义(P>0.05);治疗后,两组患者胆固醇、甘油三酯水平降低,HDL-C水平提高,且观察组优于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率少于对照组,差异有统计学意义(P<0.05)。结论常规饮食控制联合烟酸缓释胶囊及他汀类药物治疗冠心病效果显著,值得推广。
Objective To study the clinical effects of different high-density lipoprotein cholesterol (HDL-C) levels in the treatment of coronary heart disease. Methods Sixty patients with coronary heart disease were randomly divided into control group and observation group, with 30 cases in each group. The control group was treated with routine diet control. The observation group was given nicotinic acid sustained release capsules combined with statins on the basis of the control group. Compare the two groups treatment effect. Results Before treatment, there was no significant difference in cholesterol, triglyceride and HDL-C levels between the two groups (P> 0.05). After treatment, the levels of cholesterol and triglyceride decreased and HDL-C level increased in both groups The observation group was superior to the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was less than that in the control group (P <0.05). Conclusion Conventional diet control combined with nicotinic acid sustained-release capsules and statins for the treatment of coronary heart disease is effective and worth promoting.