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目的了解北京某化工企业职工脂肪肝患病情况及其影响因素,为制定防制措施提供依据。方法采用横断面调查对北京某化工企业下属13个生产厂的2 514名职工的体检资料和问卷调查情况进行分析,分析脂肪肝的患病情况及其影响因素。结果调查人群脂肪肝患病率25.3%,男性患病率(30.3%)显著高于女性(12.4%)(2=85.46,P<0.001);多因素Logistic回归分析显示:性别(OR=1.817,P<0.001)、年龄(30~40岁)(OR=1.713,P=0.007)、高血压(OR=5.848,P<0.001)、谷丙转氨酶(alanine aminotransferase,ALT)(OR=1.033,P<0.001)、吸烟(OR=7.011,P<0.001),接触职业有害因素(OR=1.565,P<0.001)等为脂肪肝的危险因素。结论应在该企业管理人员和工人人群中,尤其是在接触硫化氢、噪声等职业有害因素的30~50岁男性职工中加强关于预防和控制脂肪肝知识的宣教。
Objective To understand the prevalence and influencing factors of fatty liver in workers in a chemical enterprise in Beijing and to provide the basis for making prevention and control measures. Methods A cross-sectional survey was conducted to examine the medical check-ups and questionnaires of 2 514 employees from 13 chemical plants affiliated to a chemical enterprise in Beijing. The prevalence of fatty liver and its influencing factors were analyzed. Results The prevalence of fatty liver in the surveyed population was 25.3%, the prevalence rate in male was significantly higher than that in female (12.3% vs 12.4%, 2 = 85.46, P <0.001). Multivariate Logistic regression analysis showed that gender (OR = 1.713, P = 0.007), hypertension (OR = 5.848, P <0.001), ALT (OR = 1.033, P <0.001), smoking (OR = 7.011, P <0.001), exposure to occupational hazards (OR = 1.565, P <0.001) were risk factors for fatty liver. Conclusions Missionary education on the prevention and control of fatty liver should be stepped up among this group of business executives and workers, especially those aged 30-50 who are exposed to occupational hazards such as hydrogen sulfide and noise.