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目的：为探讨肺癌患者红细胞免疫粘附肿瘤细胞的能力。方法：用自然肿瘤红细胞花环实验和一步法肿瘤红细胞花环试验，测定26例肺癌，16例良性肺部疾病和25例老年健康人的自然肿瘤红细胞花环（NTER）、直向肿瘤红细胞花环（DTER）、促肿瘤红细胞花环（ETER）和协同肿瘤红细胞花环（ATER）率。结果：肺癌患者的NTER（1．92％±2．5％）、DTER（6．27％±5．66％）、ETER（16．85％±15．36％）和ATER（15．85％±11．06％）显著低于正常对照组和肺部良性疾病患者（P＜0．01）。结论：肺癌患者的红细胞免疫粘附实验肿瘤细胞的能力显著降低，与其红细胞C3b受体的活性低和／或缺陷及血清中补体不足有关。
Objective: To investigate the ability of RBCs to adhere to tumor cells in patients with lung cancer. METHODS: Natural nebular red cell garland (NTER), straight tumor red cell garland (DTER) of 26 cases of lung cancer, 16 cases of benign lung diseases and 25 cases of elderly healthy persons were measured by natural red blood cell rosette experiment and one-step red cell rosette test. , promote tumor red cell garland (ETER) and synergistic tumor red cell garland (ATER) rate. Results: NTER (1.92% ± 2.5%), DTER (6.27% ± 5.66%), ETER (16.85% ± 15.36%), and ATER (15.85%) in patients with lung cancer ±11.06%) was significantly lower than the normal control group and patients with benign pulmonary disease (P<0.01). CONCLUSIONS: The ability of erythrocyte immune adherence to experimental tumor cells in patients with lung cancer is significantly reduced, and is associated with low activity and/or defects in the red blood cell C3b receptor and complement deficiency in serum.