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感染人体的疱疹病毒有4种:单纯疱疹病毒(HSV,按病毒血清学可分为Ⅰ型和Ⅱ型)、水痘—带状疱疹病毒(VZV)、细胞巨化病毒(CMV)和EB病毒.其中由前两种病毒所致的单纯疱疹和带状疱疹感染在皮肤科比较常见,虽然一般来讲感染并不重,但前者易反复发作,后者常有后遗神经痛,尤其在因疾病、药物等因素所致的免疫功能不全患者,则病程长,发病次数多,甚至可导致严重的全身感染,并危及生命.但在治疗方面,由于许多抑制病毒复制的药物也将影响机体细胞的代谢,且当确诊为病毒感染时,往往复制已达高峰,多数细胞早受损伤,故迄今抗病毒药物为数不多,效果也不好.但现已知在病毒和机体细胞的代谢上是有差异的,并进行了化疗作用于病毒代谢特殊部位的研
There are 4 types of herpes viruses that infect the human body: herpes simplex virus (HSV), which can be divided into type I and type II by viral serology, varicella-zoster virus (VZV), cytomegalovirus (CMV) and Epstein-Barr virus. Which the first two viruses caused by herpes simplex and herpes zoster infections are more common in dermatology, although in general the infection is not heavy, but the former is easy to recurrent, the latter often have neuralgia, especially in patients with disease , Drugs and other factors caused by immunocompromised patients, the longer duration and frequency of occurrence, and even lead to serious systemic infection and life-threatening.But in the treatment, because many drugs that inhibit viral replication will also affect the body cells Metabolism, and when diagnosed as a viral infection, the replication has reached its peak, most of the cells have been damaged, so few antiviral drugs so far, the effect is not good.But it is known that the virus and the body cells are metabolically Differences, and the role of chemotherapy in the virus metabolism of special parts of the research