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目的:研究阿司匹林致老年人上消化道出血的临床药物特点。方法:调查2010年5月至2013年5月期间经胃镜检查技术确诊为胃溃疡、胃十二指肠溃疡并伴有出血现象的55岁以上在我院住院的患者87例。根据患者入院前一周之内有无服用阿司匹林,将患者分为服用阿司匹林组54例,以及未服用阿司匹林组33例,对两组患者的临床反应进行相关资料分析并对比。结果:阿司匹林导致老年人上消化道出血的发病高峰出现在服药一周内。()例患者在服用阿司匹林1到7天内出现消化道出血,提示在服药早期发生出血的危险性较高,随服用药物时间延长而出血量逐渐减少。结论:应提高对老年人服用阿司匹林相关性出血现象的重视,并采取相应的措施,减少因服用阿司匹林导致出血现象对老年人造成的危害。
Aims: To study the clinical characteristics of aspirin-induced upper gastrointestinal bleeding in the elderly. Methods: A total of 87 patients admitted to our hospital aged 55 years or older with gastric ulcer, gastroduodenal ulcer and hemorrhage diagnosed by gastroscopy during May 2010 to May 2013 were surveyed. Patients were divided into aspirin taking group (54 cases) and non-taking aspirin group (33 cases) according to whether aspirin was taken or not within one week before hospital admission. The clinical data of two groups were analyzed and compared. Results: Aspirin caused the peak incidence of upper gastrointestinal bleeding in the elderly within a week of taking medication. () Cases of patients taking aspirin within 1 to 7 days of gastrointestinal bleeding, suggesting that the risk of bleeding early in the medication is higher, with the medication for prolonged bleeding and gradually reduced. CONCLUSIONS: Aspirin-related hemorrhages should be emphasized in the elderly and appropriate measures should be taken to reduce the risk to the elderly of bleeding due to taking aspirin.