胃肠肽激素是近年来发展较快的胃肠学分支学科和边缘学科 ,其对消化道的吸收、分泌、运动、周身代谢和免疫起着广泛的调节作用。肾脏是胃肠肽激素主要的生物降解和清除场所。慢性肾功能衰竭时 ,由于清除减少及其它因素导致其血清浓度发生改变 ,血液透析又影响胃肠肽激素的血清水平 ,其血清水平的变化在消化道运动功能紊乱和粘膜损伤中可能起重要作用。 Gastrointestinal peptide hormone is a rapidly growing branch of gastroenterology and marginal discipline in recent years. It plays a broad regulatory role in gastrointestinal absorption, secretion, exercise, whole body metabolism and immunity. The kidneys are the major sites of biodegradation and clearance of gastrointestinal peptide hormones. Chronic renal failure, due to reduced clearance and other factors lead to changes in serum concentrations, hemodialysis and gastrointestinal hormone levels affect serum levels of serum levels change may play an important role in gastrointestinal disorders and mucosal injury .