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目的 :探讨慢性乙型肝炎 (慢乙肝 )患者血清中各年龄组Fe3 + 、Mg2 + 、Cu2 + 、Zn2 + 的含量变化。方法 :用比色法检测 12 6例慢乙肝患者及 130名健康者血清Fe3 + 、Mg2 + 、Cu2 + 、Zn2 + 。结果 :12 6例慢乙肝患者的Fe3 + 、Mg2 + 、Cu2 + 、Zn2 + 与 130名健康者的含量进行比较 ,前者的Fe3 + 、Mg2 + 、Zn2 + 显著低于后者 (P <0 .0 1) ;而前者的Cu2 + 显著高于后者 (P <0 .0 1)。根据年龄分组把 12 6例分为青、中、老三组 ,结果显示各年龄组患者的Fe3 + 、Mg2 + 和Zn2 + 含量均较对照组低 (P <0 .0 1) ,而Cu2 + 则均高于对照组 (P <0 .0 1)。结论 :检测血清Fe3 + 、Mg2 + 、Cu2 + 、Zn2 + 的含量 ,有助于慢乙肝的诊断及治疗 ,并可随时对患者进行动态的预后评价。
Objective: To investigate the changes of serum Fe3 +, Mg2 +, Cu2 + and Zn2 + in serum of patients with chronic hepatitis B (chronic hepatitis B). Methods: Serum Fe3 +, Mg2 +, Cu2 + and Zn2 + were detected by colorimetric method in 126 patients with chronic hepatitis B and 130 healthy controls. Results: The contents of Fe3 +, Mg2 +, Cu2 +, Zn2 + in 12 6 chronic hepatitis B patients and 130 healthy people were significantly lower than those in the latter (P <0. 0 1), while the former Cu2 + was significantly higher than the latter (P <0.01). According to the age group, 12 6 cases were divided into three groups: young, middle and old. The results showed that the Fe3 +, Mg2 + and Zn2 + contents in all age groups were lower than those in the control group (P <0.01) Were higher than the control group (P <0.01). Conclusion: The detection of serum levels of Fe3 +, Mg2 +, Cu2 + and Zn2 + is helpful for the diagnosis and treatment of chronic hepatitis B. The prognosis of patients can be evaluated dynamically at any time.