论文部分内容阅读
目的探讨巨细胞病毒感染的临床特点及治疗。方法对2007年1月至2008年12月在50例经血清学检测确诊CMV感染的婴幼儿的临床资料进行分析。结果支气管肺炎24例(48%),高胆红素血症20例(40%),中枢神经系统损害16例(32%),所有病例均给予更昔洛韦(GCV)治疗,支气管肺炎治愈16例,好转6例,未愈2例;高胆红素血症治愈7例好转12例,未愈1例;中枢神经系统损害治愈1例,好转8例,未愈7例。结论婴儿CMV感染以支气管肺炎、高胆红素血症和中枢神经系统损害为多见,血清特异性CMV-IgM抗体阳性为CMV感染的实验室诊断依据,GCV是治疗CMV婴儿感染的首选药物。
Objective To investigate the clinical features and treatment of cytomegalovirus infection. Methods From January 2007 to December 2008 in 50 cases of serological detection confirmed CMV infection in infants and young children’s clinical data were analyzed. Results Bronchial pneumonia in 24 cases (48%), hyperbilirubinemia in 20 cases (40%), central nervous system damage in 16 cases (32%), all cases were given ganciclovir (GCV) treatment, bronchopneumonia cure 16 cases improved 6 cases, healed 2 cases; hyperbilirubinemia cured 7 cases improved in 12 cases, healed 1 case; central nervous system damage was cured in 1 case, improved in 8 cases, healed in 7 cases. Conclusion CMV infection in infants is more common in bronchial pneumonia, hyperbilirubinemia and central nervous system damage. Serum-specific CMV-IgM antibody is the laboratory diagnostic evidence of CMV infection. GCV is the first choice of drug for CMV infection.