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目的评价普通体表心电图 T 波峰-末间期(Tpeak-Tend,Tp-e)作为 Brugada 综合征(Brs)一种新的危险分层指标。方法将23例男性 BrS 患者与20例男性阵发性室上性心动过速(PSVT)患者的体表心电图 Tp-e 值进行比较。结果 Tp-e 平均值,BrS 组为(109.57±22.86)ms,PSVT 组为(88.50±13.08)ms,两组间差异有统计学意义(P<0.05)。BrS 组中16例患者并发心脏事件(晕厥、临床记录心室颤动、电生理诱发心室颤动),7例患者无上述心脏事件,心脏事件组的 BrS 患者 Tp-e 值较无心脏事件组 BrS 患者和 PSVT 组患者显著延长(P<0.05),而无心脏事件组 BrS 患者与PSVT 组患者 Tp-e 值间差异无统计学意义(P>0.05)。结论 Tp-e 值延长(Tp-e≥120 ms)可作为BrS 患者一种新的无创性危险分层指标。
Objective To evaluate Tpeak-Tend (Tp-e), a general body surface electrocardiogram, as a new risk stratification index for Brugada syndrome (Brs). Methods Electrocardiographic Tp-e values of 23 male patients with BrS and 20 patients with paroxysmal supraventricular tachycardia (PSVT) were compared. Results The mean Tp-e was (109.57 ± 22.86) ms in the BrS group and (88.50 ± 13.08) ms in the PSVT group, with significant difference between the two groups (P <0.05). Sixteen patients in the BrS group had cardiac events (syncope, clinical recording of ventricular fibrillation, and electrophysiological-induced ventricular fibrillation). None of the seven patients had the above-mentioned cardiac events. The Brp patients with BrS in the cardiac event group had significantly higher Tp-e values than BrS patients without cardiac events and PSVT group was significantly prolonged (P <0.05), but there was no significant difference in Tp-e between patients without PSS group and PSS group (P> 0.05). Conclusions Tp-e prolongation (Tp-e≥120 ms) may be a new non-invasive risk stratification index for patients with BrS.