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目的探讨血清脑钠肽(BNP)和心肌肌钙蛋白I(cTNI)在急性心肌梗死(AMI)患者血浆中的表达水平及其相关性。方法将2011年3月-2013年3月我院AMI患者33例作为病例组,无冠状动脉疾病史健康查体者40例作为对照组。检测上述两组患者血清BNP与cTNI水平。结果病例组血浆BNP显著高于对照组(P<0.01),病例组血浆cTNI显著高于对照组(P<0.001)。病例组血浆BNP与cTNI之间存在正相关性,Spearson相关系数r为0.72(P<0.01)。结论 AMI患者血清BNP和cTNI显著高于健康人,且两指标存在明显相关性。
Objective To investigate the plasma levels of serum brain natriuretic peptide (BNP) and cardiac troponin I (cTNI) in patients with acute myocardial infarction (AMI) and their correlation. Methods From March 2011 to March 2013, 33 patients with AMI in our hospital were selected as the case group and 40 patients without history of coronary artery disease as the control group. Serum BNP and cTNI levels were measured in the two groups. Results The plasma BNP level in case group was significantly higher than that in control group (P <0.01). The plasma cTNI in case group was significantly higher than that in control group (P <0.001). There was a positive correlation between plasma BNP and cTNI in case group, and Spearson correlation coefficient r was 0.72 (P <0.01). Conclusions The serum BNP and cTNI in patients with AMI were significantly higher than those in healthy people, and there was a significant correlation between the two indexes.