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目的探讨运动训练对老年冠心病患者左心室舒张功能的影响。方法 64例老年冠心病患者随机分为运动训练组和常规治疗组,各32例,均接受12周相同的冠心病药物治疗,运动训练组同时进行运动训练。另选择30例健康老年人为正常对照组。超声心动图评估左心室舒张功能和收缩功能,6min步行距离试验评估运动耐量。结果治疗前,与正常对照组相比,其他两组患者左心室舒张晚期二尖瓣峰值血流速度(A)明显增高(P<0.05),左心室舒张早期二尖瓣峰值血流速度(E)、E/A参数明显降低(P<0.05);左心室收缩功能均在正常范围。治疗后,常规治疗组和运动训练组患者E、A、E/A参数均有所改善,6min步行距离均有增加,运动训练组E、A、E/A参数优于常规治疗组(P<0.01);运动训练组较常规治疗组增加更显著(P<0.01);左心室收缩功能无明显改变(P>0.05)。结论运动训练能改善老年冠心病患者的左心室舒张功能和运动耐量。
Objective To investigate the effect of exercise training on left ventricular diastolic function in elderly patients with coronary heart disease. Methods Sixty-four elderly patients with coronary heart disease were randomly divided into exercise training group and conventional treatment group. Each group of 32 patients received the same coronary heart disease medication for 12 weeks. The exercise training group also exercised at the same time. Another 30 healthy elderly were selected as normal control group. Echocardiographic assessment of left ventricular diastolic function and systolic function, 6min walking distance test to assess exercise tolerance. Results Before treatment, compared with the normal control group, the peak velocities of mitral valve in the other two groups were significantly increased (P <0.05), and the peak velocities of mitral valve in the early diastole of left ventricle (E ), E / A parameters decreased significantly (P <0.05); left ventricular systolic function were in the normal range. After treatment, the parameters of E, A and E / A in both the conventional treatment group and the exercise training group improved and the distance of 6min walk increased. The parameters of E, A and E / A in exercise training group were superior to the conventional treatment group (P < 0.01). The exercise training group increased more significantly than the conventional treatment group (P <0.01), while the left ventricular systolic function did not change significantly (P> 0.05). Conclusion Exercise training can improve left ventricular diastolic function and exercise tolerance in elderly patients with coronary heart disease.