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目的 探讨感染性腹泻致全身炎症反应综合征(SIRS)患儿血清C反应蛋白、电解质的变化及临床意 义。方法 对63例感染性腹泻患儿其中34例SIRS患儿和29例非SIRS患儿应用全自动散射比浊法测定血清 CRP及电解质变化,并与32例健康对照组比较。结果 SIRS患儿血清CRP含量明显高于非SIRS组和对照组, 存在显著性差异(P<0.01),而且电解质紊乱情况严重。结论 CRP在感染性腹泻引起的SIRS中升高明显,对 SIRS的预后和抗生素的合理应用提供了理论依据。
Objective To investigate the changes of serum C-reactive protein and electrolytes in children with systemic inflammatory response syndrome (SIRS) caused by infectious diarrhea and its clinical significance. Methods Serum CRP and electrolytes were measured in 34 children with SIRS and 29 non-SIRS children with infectious diarrhea by automatic scatter turbidimetric method and compared with 32 healthy controls. Results Serum CRP levels in children with SIRS were significantly higher than those in non-SIRS and control groups (P <0.01), and electrolyte imbalance was serious. Conclusion CRP is significantly elevated in SIRS caused by infectious diarrhea and provides a theoretical basis for the prognosis of SIRS and rational use of antibiotics.