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J H Bertoglio文章:通过一些细胞表面受体的表达可以对人类T淋巴细胞进行鉴定。近年,对这些标志(E-玫瑰花受体、Tμ与TΥ受体)以及由异种抗血清或单克隆抗体(单抗,下同)所鉴定的抗原的研究,使带有一定表型的功能亚群得到鉴定。例如,业已充分证实的OKT系统中的单抗能够确定T细胞系分化过程中的各个阶段,其中有些与功能活性有关:周围血淋巴细胞的细胞毒性/抑制性亚群表达OKT8抗原,而OKT4抗原只表达在诱导性/辅助
J H Bertoglio Article: Human T lymphocytes can be identified by the expression of some cell surface receptors. In recent years, studies on these markers (E-rose receptor, Tμ and T-receptor) and antigens identified by heterologous antisera or monoclonal antibodies (monoclonal antibodies, the same shall apply hereinafter) have the function of a certain phenotype Subgroups were identified. For example, the well-established OKT system’s mAbs identify various stages of T-cell lineage differentiation, some of which are associated with functional activity: the OKT8 antigen is expressed by the cytotoxic / inhibitory subpopulation of peripheral blood lymphocytes and the OKT4 antigen Only expressed in inducible / accessory