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检测５０例胃癌、２０例良性胃疾病病灶和１４例正常胃粘膜组织中雌激素受体（ＥＲ）、雌二醇（Ｅ２）和睾酮（Ｔ）含量。结果显示：胃癌组织ＥＲ阳性率为３２．０％，分化不良型高于分化型（Ｐ＜０．０５），ＢｏｒｒｍａｎｎⅢ、Ⅳ型高于Ⅰ、Ⅱ型（Ｐ＜０．０５）。由此表明，ＥＲ测定对估计患者的预后和术后内分泌治疗具有一定意义。Ｅ２在胃癌、良性胃疾病灶和正常胃粘膜中的含量均无显著差异，但胃癌组Ｔ含量及Ｔ／Ｅ２值显著高于良性胃疾病组和正常胃粘膜组（Ｐ＜０．０５）。提示胃癌的发生可能与Ｅ２和Ｔ在体内失衡有一定的关系。胃癌组织中Ｅ２和Ｔ水平与ＥＲ阳性组和阴性组之间无显著差异。
The levels of estrogen receptor (ER), estradiol (E2) and testosterone (T) in 50 cases of gastric cancer, 20 cases of benign gastric lesions and 14 cases of normal gastric mucosa were detected. The results showed that the positive rate of ER in gastric cancer tissues was 32.0%. The poorly differentiated type was higher than the differentiated type (P<0.05). Borrmann III and Type IV were higher than those of Type I and Type II (P<0.05). This shows that ER determination has a certain significance for estimating the prognosis of patients and postoperative endocrine therapy. There was no significant difference in the content of E2 in gastric cancer, benign gastric lesions and normal gastric mucosa, but T content and T/E2 value in gastric cancer group were significantly higher than those in benign gastric disease group and normal gastric mucosa group (P<0.05). It is suggested that the occurrence of gastric cancer may have a certain relationship with E2 and T imbalance in the body. There was no significant difference between E2 and T levels in gastric cancer tissues and ER positive and negative groups.