口服甾体避孕药物的试制成功是近代医学中的一件大事,因为它不仅为世界上若干地区数百万妇女解决了避孕问题,更重要的是:在研究这个问题的过程中所得到的知识,又充实了生殖生理的内容,为进一步明确人类的生育问题提供了宝贵资料;因此有人认为口服避孕药的发现,无论从理论价值上来看,或是从实际意义上来看,不亚于抗菌素的发现。早在1921年,人们即已知道天然性激素可以抑制排卵,使动物失去生育能力。但当时为何未能用以作为人类避孕的方法呢?主要因为天然激素中还存在着一些缺点,而且口服效用不大。十余年来,各国科学家对除去激素中不良因秦,提高其避孕效率,使它变成口服等方面作了不少努力,进行了大量研究,格于1950年前后,合成了一系列具有避孕效果、能口服的甾族化合物。自1956年起,Pincus 和 Tyler 等先后在 Los Angels 及Puerto Rico 等地开展了大规模的临床应用,截至目前为止,应用此种方法的妇女,在欧、 The successful trial of oral steroid contraceptives is a major undertaking in modern medicine because it not only addresses the issue of contraception for millions of women in several parts of the world, but more importantly, the knowledge gained in the study of the problem , And enriched the content of reproductive physiology, in order to further clarify the issue of human reproduction provides valuable information; therefore, some people think that the discovery of oral contraceptives, both in theoretical terms, or in practical terms, as much as the antibiotic Find. As early as 1921, people already know that natural hormones can inhibit ovulation, so that animals lose their fertility. However, why was it not used as a method of human contraception? The main reason is that there are some shortcomings in natural hormones, and the oral effect is not great. For more than ten years, scientists from all over the world have done a lot of research on eliminating the bad hormone in Qin, improving the efficiency of its contraception, and making it into oral administration. A great deal of research has been done. In 1950, a series of contraceptives with contraception Effect, can be orally administered steroids. Since 1956, Pincus and Tyler have carried out large-scale clinical applications in places such as Los Angels and Puerto Rico successively. So far, women applying this method have been studying in Europe,