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目的:观察泮托拉唑钠联合艾灸治疗慢性浅表性胃炎的疗效和安全性。方法:将104例慢性浅表性胃炎患者随机分为观察组和对照组各52例,对照组给予静滴泮托拉唑钠注射液,观察组在对照组基础上联合艾灸治疗。疗程均为两周。观察两组患者治疗前后症状评分变化,比较两组患者的临床疗效、药品不良反应及复发率。结果:观察组显效率和总有效率分别为80.8%和96.2%,临床疗效明显优于对照组(P<0.01);治疗后症状评分及其差值均显著优于对照组(P<0.01);6个月后复发率低于对照组(P<0.05)。两组药品不良反应发生率差异无统计学意义(P>0.05)。结论:泮托拉唑钠联合艾灸治疗慢性浅表性胃炎,可有效缓解患者临床症状,提高疗效,降低复发率,优于单用西药治疗,具有广阔的临床应用前景。
Objective: To observe the efficacy and safety of pantoprazole sodium combined with moxibustion in the treatment of chronic superficial gastritis. Methods: A total of 104 patients with chronic superficial gastritis were randomly divided into observation group (52 cases) and control group (52 cases). The control group was given intravenous pantoprazole sodium injection. The observation group was treated with moxibustion on the basis of the control group. The course of treatment is two weeks. The changes of symptom score before and after treatment were observed in two groups of patients. The clinical efficacy, adverse drug reactions and recurrence rate were compared between the two groups. Results: The markedly effective rate and total effective rate in the observation group were 80.8% and 96.2%, respectively, and the clinical efficacy was significantly better than that in the control group (P <0.01). After treatment, the symptom score and the difference were significantly better than those in the control group (P <0.01) The recurrence rate after 6 months was lower than that of the control group (P <0.05). There was no significant difference in the incidence of adverse drug reactions between the two groups (P> 0.05). Conclusion: The combination of pantoprazole sodium and moxibustion in the treatment of chronic superficial gastritis can effectively relieve the clinical symptoms, improve the curative effect and reduce the recurrence rate, which is superior to the single western medicine treatment and has a broad clinical application prospect.