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目的 探讨糖尿病和贫血患者血浆中乳酸质量浓度与正常人和献血员间的关系 .方法 利用气相色谱对血浆乳酸值进行外标法测定 .实验分 4组 :A组 :糖尿病患者 7例 (男4,女 3,年龄 30～ 6 0岁 ) ,B组 :贫血患者 9例 (男 6 ,女 3,年龄2 0～ 6 0岁 ) ,C组 :正常人 15例 (男 9,女 6 ,年龄 2 0～ 5 0岁 ) ,D组 :献血员 2 8例 (男 19,女 9,年龄 2 0～ 30岁 ) .结果 糖尿病和贫血患者、正常人和献血员血浆中乳酸质量浓度分别为(4 72± 2 15 ) mg· L- 1 ,(340± 12 5 ) mg· L- 1 ,(130± 31) mg·L- 1 和 (147± 46 ) mg· L- 1 .糖尿病和贫血患者血浆乳酸质量浓度明显高于正常人和献血员 (P<0 .0 1) .结论 我们测定的乳酸值可作为糖尿病和贫血患者临床诊断指标之一 .
Objective To investigate the relationship between the concentration of lactic acid in plasma and patients with normal blood and blood donors in patients with diabetes and anemia.METHODS Gas chromatography was used to determine the value of plasma lactate by external standard method.The experiment was divided into 4 groups: group A: 7 diabetic patients (male 4 , Female 3, age 30-60 years), group B: 9 cases of anemia (male 6, female 3, age 20 ~ 60), group C: 15 cases of normal (male 9, female 6, age 2 0 ~ 5 0 years old), group D: blood donors 28 cases (male 19, female 9, age 20 ~ 30 years) .Results The plasma concentrations of lactate in diabetic and anemia patients, normal persons and blood donors were 4 72 ± 2 15) mg · L -1, (340 ± 125) mg · L -1, (130 ± 31) mg · L -1, and (147 ± 46) mg · L -1 in patients with diabetes and anemia The plasma concentration of lactic acid was significantly higher than that of normal people and blood donors (P <0.01) .Conclusion Our determination of lactic acid can be used as one of the clinical diagnostic indicators of patients with diabetes and anemia.