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下丘脑内钙离子与发热调控机制间的关系近年来日益受到广泛的重视。Pami最近的实验结果揭示:由内毒素或IL-1β引起发热的家兔,其脑脊液中的Ca2+浓度伴随着直肠温度升高而呈持续显著升高,显然,下丘脑内钙离子的代谢变化在发热的调节中起着重大的作用。但发热时
In recent years, the relationship between hypothalamic intracellular calcium and fever regulation has been paid more and more attention. Recent experimental results from Pami revealed that the Ca2 + concentration in cerebrospinal fluid of rabbits with endotoxemia or IL-1β-induced fever continued to increase significantly with increasing rectal temperature. Obviously, the metabolic changes of calcium in hypothalamus Regulation of fever plays a significant role. But when fever