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近年来，格兰氏阳性球菌，尤其是耐甲氧西林的金黄色葡萄球菌、表皮葡萄球菌和肠球菌引起的严重肺部感染和肾盂肾炎逐渐增多。特别是老年患者，由于其抵抗力差，基础病多以及反复使用多种抗生素等原因，使老年人发生此类感染的人数大大增加，而且往往病情严重［１］。万古霉素?
In recent years, Gram-positive cocci, especially methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis and enterococci cause serious pulmonary infection and pyelonephritis gradually increased. Especially in elderly patients, the number of elderly people who suffer from such infections is greatly increased and often presents with serious illness due to their poor immunity, basic diseases and the repeated use of multiple antibiotics [1]. Vancomycin?