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目的:研究六味地黄丸加减对乳腺癌化疗后自觉症状群的影响。方法:采用药物对60例病例的进行为期2月的干预,研究其治疗中医证候改善率,以及治疗前后症状改善程度比较。结果:①治疗后中医证候改善情况为:临床痊愈3例(5%),显效35例(58%),有效20(33%)例,无效4(7%)例。②治疗前后腰膝酸软、潮热、盗汗、眩晕、耳鸣、心烦、失眠等症状比较差异具有显著性(P<0.05或P<0.01)。治疗后口燥咽干症状改善比较差异无显著性(P>0.05)。结论:六味地黄丸加减方可以有效改善乳腺癌化疗后自觉症状群。
Objective: To study the effect of Liuweidihuangwan addition and subtraction on the symptoms of breast cancer after chemotherapy. Methods: A total of 60 cases were treated with drugs for 2 months. The improvement rate of TCM syndromes and the improvement of symptoms before and after treatment were studied. Results: ①The improvement of TCM syndromes after treatment was as follows: 3 cases (5%) were clinically cured, 35 cases (58%) were effective, 20 (33%) effective and 4 (7%) ineffective. ② Before and after treatment, there were significant differences in symptoms such as waist and knees, hot flashes, night sweats, dizziness, tinnitus, upset and insomnia (P <0.05 or P <0.01). There was no significant difference in the improvement of the symptoms of dry mouth and throat after treatment (P> 0.05). Conclusion: Liuweidihuangwan addition and subtraction can effectively improve the symptoms of breast cancer after chemotherapy group.