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目的:分析甲泼尼龙治疗毛细支气管炎(简称毛支炎)的疗效。方法:将64例我科确诊为毛支炎的患儿按就诊先后随机抽签分为治疗组34例和对照组30例,在综合治疗的基础上,对照组给予地塞米松0.25～0.5 mg/(kg.d),分2次静脉滴注;治疗组给予甲泼尼龙2 mg/(kg.次),2次/d静脉滴注,疗程5 d左右。结果:治疗组总有效率91.2%,对照组总有效率60.0%,治疗组总有效率显著高于对照组,差异有统计学意义(χ2=8.6,P<0.01)。治疗组患儿在喘憋、肺部哮鸣音、湿性啰音消失时间及住院天数方面与对照组比较明显缩短,差异有统计学意义(P<0.01)。结论:甲泼尼龙治疗毛支炎疗效明显优于地塞米松。
Objective: To analyze the curative effect of methylprednisolone on bronchiolitis. Methods: A total of 64 children with mycoplasma in our department were randomly divided into treatment group (34 cases) and control group (30 cases). On the basis of comprehensive treatment, the control group was given dexamethasone 0.25-0.5 mg / (kg.d). The patients in the treatment group were given methylprednisolone 2 mg / (kg) twice a day for about 5 days. Results: The total effective rate was 91.2% in the treatment group and 60.0% in the control group. The total effective rate in the treatment group was significantly higher than that in the control group (χ2 = 8.6, P <0.01). Compared with the control group, the treatment group was significantly shorter than the control group in asthmatic wheezing, wheezing of the lungs, disappearance of wet rales and days of hospitalization. The difference was statistically significant (P <0.01). Conclusion: Methylprednisolone is superior to dexamethasone in the treatment of bronchiolitis.