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[目的]探讨超声引导下经皮粗针穿刺活检(core needle biopsy,CNB)在乳腺癌诊断和治疗中的应用价值。[方法]回顾性分析189例临床可疑乳腺肿块经CNB组织病理学检查结果以及临床资料。[结果]189例患者中,CNB阳性结果119例(其中低估者4例),阴性结果70例(其中假阴性4例),没有假阳性结果。本组病例中CNB确诊率93.5%,假阴性率6.5%(包括4例低估病例),并有不同比例患者接受新辅助化疗和保乳手术。[结论]超声引导下乳腺可疑肿块CNB病理学检查准确率高、安全、可靠,能满足目前原发性乳腺癌综合治疗发展的需要,在乳腺癌的诊断和治疗中有很高的应用价值。
[Objective] To investigate the value of ultrasound-guided core needle biopsy (CNB) in the diagnosis and treatment of breast cancer. [Methods] The clinical suspicious breast masses of 189 cases with CNB histopathological examination and clinical data were retrospectively analyzed. [Results] Of the 189 patients, 119 were positive for CNB (4 were underestimated) and 70 were negative (4 for false negative). There was no false positive result. The diagnosis of CNB in this group of patients was 93.5%, false negative rate of 6.5% (including 4 cases of underestimation), and a different proportion of patients receiving neoadjuvant chemotherapy and breast conserving surgery. [Conclusion] The ultrasound-guided suspicious lumps of CNB have high accuracy, safety, reliability and can meet the needs of the development of comprehensive treatment of primary breast cancer. It has high value in the diagnosis and treatment of breast cancer.