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用ELISA法检测了62例妇女血清EmAb和SIL－2R水平，其中内膜异位症患者34例（内异组），妇科良性病组15例（妇病组）、正常健康妇女13例（正常对照组）。结果EmAb阳性率内异组（61.7％）明显高于妇病组（20．0％）和正常对照组（7．6％），（P＜0.01）。SIL－2R内异组（872．28±74.47）明显高于妇病组（265.53±66．42）及正常对照组（245.54±53.46），（P＜0.01）。用EmAb和SIL－2R诊断子宫内膜异位症敏感性分别为61.7％和79.4％；特异性分别为80．0％和57.1％。二者综合分析敏感性和特异性分别为52.9％和92.8％。血清EmAb和SIL-2R联合测定有助于子宫内膜异位症的诊断和鉴别。
Sixty-two women were tested for serum levels of EmAb and SIL-2R by ELISA, including 34 patients with endometriosis (endometriosis), 15 patients with gynecologic benign disease (women with disease) and 13 healthy women (normal Control group). Results The positive rate of EmAb in endometriosis group (61.7%) was significantly higher than that in gynecopathy group (20.0%) and normal control group (7.6%) (P <0.01). The level of SIL-2R was significantly higher in women with rheumatoid arthritis (872.28 ± 74.47 vs 265.53 ± 66.42 vs 245.54 ± 53.46, P <0.01). The sensitivity of using EmAb and SIL-2R to diagnose endometriosis were 61.7% and 79.4% respectively; the specificity was 80.0% and 57.1% respectively. The sensitivity and specificity of the two methods were 52.9% and 92.8% respectively. Serum EmAb and SIL-2R combined determination of endometriosis contribute to the diagnosis and identification.