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目的观察乳酸菌素治疗小儿急性腹泻的疗效。方法用随机数字表,小儿急性腹泻121例分为2组:口服乳酸菌素加口服补液盐组(试验组)52例,每次给予乳酸菌素片0.2～0.6 g,每日3次,口服补液盐120～150 mL.kg-1;单纯口服补液盐组(对照组)69例,口服补液盐120～150 mL.kg-1。记录2组患儿每日腹泻次数和腹泻持续天数。结果试验组与对照组,腹泻持续时间分别为(3.3±2.2),(5.1±3.1)d,住院天数分别为(4.2±1.6),(6.3±2.3)d,医疗费分别为(1801.1±621.1),(2491.6±681.9)元,2组比较差异均有统计学意义(均P<0.05)。结论乳酸菌素治可以降低小儿腹泻持续时间,减少住院天数和住院费用。
Objective To observe the efficacy of lactobacillus in children with acute diarrhea. Methods A total of 121 children with acute diarrhea were randomly divided into 2 groups: oral lactic acid bacteria plus oral rehydration salt group (experimental group), 52 patients were given lactic acid bacteriocin tablets 0.2-0.6 g three times a day orally 120 ~ 150 mL.kg-1; oral rehydration salt group (control group) 69 cases, oral rehydration salt 120 ~ 150 mL.kg-1. The daily number of diarrhea and the duration of diarrhea in two groups were recorded. Results The duration of diarrhea in trial group and control group were (3.3 ± 2.2) days and (5.1 ± 3.1) days respectively, and the hospitalization days were (4.2 ± 1.6) and (6.3 ± 2.3) days respectively, and the medical expenses were (1801.1 ± 621.1 ), (2491.6 ± 681.9) yuan, the difference between the two groups was statistically significant (P <0.05). Conclusion Lactic acid treatment can reduce the duration of diarrhea in children, reduce hospital stay and hospitalization costs.